In the last 2 years, I stayed in motels from Las Vegas to New York, along route 70 North and Route 40 South. I usually use the "Choice" line or the lower end, because I know that I just need to get some sleep and not try to make it my home. I carry LYSOL, my own pillow, my own sheets, wash cloth and towels. I take the bedspread, roll up, and use to prop up my feet when I sleep. I never use it to sleep under. If I need to cover up, I have my own sheet to do so. I have these things with me, because I drive, most of the time. But, when I fly, believe me, I have my can of LYSOL packed in my bag and spray everything down, before I use it.
I would suggest that we all do the same thing.
Happy Traveling!